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Methods

Data collection


Interviews are conducted by trained health workers using a standardized questionnaire. The questionnaire is designed to gather data on lifestyle, reproductive history, physical activity/inactivity, and diet for both cases and controls. Blood and spot urine samples are collected, and height, weight, waist circumference, and hip circumference are measured for all participants. In addition, dual-energy X-ray absorptiometry (DXA) and computed tomography (CT) are used to obtain more-accurate estimates of body composition (lean tissue vs fat).